Answer 2 for NUR 550 Consider ecological and global issues, social determinants of health, principles of genetics, and genomics

Answer 2 for NUR 550 Consider ecological and global issues, social determinants of health, principles of genetics, and genomics

When considering ecological and global issues, social determinants of health, genetics, and genomics, translational research methods are the key to moving new therapies into clinical practice – easing the burden of global diseases and disorders. Thus, translational research examines how scientific work can be moved into clinical practice to inspire evidence-based practice changes that benefit society (“Translation research”, 2020).
By recognizing how social determinants such as economic stability, educational quality, educational levels, health care access, and quality impact populations, researchers can be better positioned to understand how to address, reduce, and prevent certain disorders and diseases of specific populations in the future.
According to DeNisco, 2019, p.193, incidences of cancer around the world are rising. The pain and suffering stemming from cancer and other diseases and health disorders is a motivational factor that may influence science researchers into utilizing translational research to translate new treatments, medications, and technological products into clinical practice in a timely manner.

Currently, an area of research – called genetic engineering, is in place to assist in customizing and individualizing patient care (DeNisco, 2019, p. 392). Thus, genetic engineering is where the genome (an organism’s DNA and all of its genes), is plotted to provide an understanding of individual DNA, which also analyzes the impact of external factors (genomics), (DeNisco, 2019, p. 392).
Hence, in their article, Ren et al., 2022 discussed that they applied translational research to pave the way in developing new generation treatments to treat inherited retinal disease (IRD), where their approaches entered into clinical phases of development, and some have translated into approved products that assist in manifesting improved patient outcomes related to IRD.

References

DeNisco, S. M. (2019). Advanced Practice Nursing: Essential knowledge for the profession (3rd ed.). Jones & Bartlett Learning.

Ren, D., Fisson, S., Dalkara, D., & Ail, D. (2022). Immune Responses to Gene Editing by Viral and Non-Viral Delivery Vectors Used in Retinal Gene Therapy. Pharmaceutics, 14(9), N.PAG. https://10.3390/pharmaceutics14091973

Translation research. (2020, February 24). Centers for Disease Control and Prevention. https://www.cdc.gov/niosh/topics/translationresearch/default.html